The weapon modifier perks called "Chemical Imbalance" and "Enchanted Matrix" do not work. You can add 1 million barrels to the table and not one of them will pop the chemical imbalance perk. You can also enchant 500 items and the enchanted matrix will not dupe the weapon.
Along with this, Artifacts are either way too rare or are bugged to where you cant enchant them anymore. This can be shown by the below chart which shows the results of almost 2300 enchantments.
By these metrics, you will receive an artifact every 2270 enchants. The issue comes into the pricing for enchanting. It is extremely expensive when done in large amounts. The chart above shows 2270 enchants done, which if you bought the materials to do it all at market price, it would cost you approximately 56,120,000. While you would only make back 33,560,000. This results in a net loss of 22,560,000.